■ Sight Sciences, Inc., announced 36-month post-surgery follow-up results of the Omni Surgical System demonstrating that, alone, it delivers safe, consistent, and durable results in adult patients with open-angle glaucoma. Canaloplasty followed by trabeculotomy using Omni achieved a mean reduction in IOP of at least 20% for all 26 patients (38 eyes) at 36 months, according to a news release. Patients’ mean preoperative IOP after medication washout and surgery decreased from 24.6±3.2 mmHg to 14.5±1.7 mmHg at 12 months, 14.2±2.0 mmHg at 24 months, and 15.0±1.9 mmHg at 36 months. The mean number of IOP-lowering medications was reduced from 1.9±0.7 to 0.4±0.6 at 12 months, 0.6±0.7 at 24 months, and 0.5±0.7 at 36 months. Postoperative IOP and medication use reduction at 12 months remained consistent over 3 years.
“The results consistently show the minimally invasive procedure has the potential to offer long-standing benefits for patients with open-angle glaucoma,” said Karsten Klabe, MD, principal investigator, head surgeon of Breyer, Kaymak & Klabe Augenchirurgie. “Most patients experienced an IOP reduction of at least 20% and required significantly less medication, meeting the study’s objective. By effectively reducing IOP and the medication burden, the OMNI Surgical System is transforming how glaucoma is cared for in both combination cataract and standalone glaucoma patients.”