Which Patients Benefit Most From Repeat SLT?

A retrospective observational study of more than 279,000 eyes may help guide patient selection for repeat SLT.

By: Wendy Liu, MD, PHD,

Glaucoma Physician February 20, 2026

5 Key Takeaways

1

A study of over 279,000 eyes assessed the efficacy of repeat selective laser trabeculoplasty (SLT) using the IRIS Registry.
2

The overall response rate for repeat SLT was 11%, with an average intraocular pressure reduction of 2.5 mmHg.
3

Higher baseline intraocular pressure significantly correlated with better response rates to repeat SLT.
4

Patients who initially responded to SLT had an 80% response rate, compared to only 7% for those who did not.
5

Socioeconomic factors, such as Medicaid insurance and type 2 diabetes, were linked to lower response rates to repeat SLT.

Wendy Liu

Affiliations: Stanford University

Specialties: Ophthalmology

Bio: Wendy Liu, MD, PhD, is affiliated with Stanford University and presented research at the American Glaucoma Society meeting on repeat selective laser trabeculoplasty using IRIS Registry data. Her work focuses on glaucoma and real-world outcomes research in ophthalmology. At the 2026 meeting, she discussed a large retrospective analysis examining which patients benefit most from repeat SLT, with attention to intraocular pressure response and baseline clinical characteristics. Her recent indexed publications also include work in emergency medicine doctoral training and virologic serosurveillance.

PentaVision

Glaucoma Physician

Which Patients Benefit Most From Repeat SLT?

5 Key Takeaways

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