Nutritional Supplementation in Glaucoma

Evidence points to neuroprotective and vasoregulatory effects of dietary supplements and nutrients in glaucoma management.

By: Cecily L. Kaufmann, BSN, Samantha Goldburg, MD, Rachel Chapman, Mary Qiu, MD,

Glaucoma Physician March 1, 2026 Page(s): 19-21

Clinical Report: Nutritional Supplementation in Glaucoma

Overview

This report reviews the potential role of nutritional supplementation in managing glaucoma, highlighting the neuroprotective and vasoregulatory effects of specific dietary nutrients. While not a replacement for standard treatments, certain supplements may enhance therapeutic outcomes.

Background

Glaucoma is a multifactorial disease characterized by optic nerve damage, often associated with elevated intraocular pressure (IOP). As patients increasingly inquire about complementary therapies, understanding the potential benefits of dietary modifications and supplements becomes essential. Current research suggests that specific nutrients may target mechanisms involved in glaucoma progression, including oxidative stress and neurodegeneration.

Data Highlights

No numerical data presented in the article.

Key Findings

Antioxidants like vitamin C may reduce the odds of glaucoma when consumed in adequate amounts.
Higher dietary intake of vitamin A has been linked to a lower incidence of glaucoma in women.
Oral vitamin E supplementation has shown potential to improve ocular blood flow in glaucoma patients.
Lutein and zeaxanthin supplementation may reduce retinal ganglion cell loss.
Saffron extract supplementation was associated with a mean IOP reduction in patients with primary open-angle glaucoma.

Clinical Implications

Healthcare professionals should consider discussing dietary modifications and nutritional supplements with glaucoma patients as adjuncts to standard therapy. While these interventions are not replacements for established treatments, they may provide additional benefits in managing the disease.

Conclusion

Nutritional supplementation presents a promising area of exploration in glaucoma management, warranting further research to establish definitive clinical guidelines and recommendations.

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