Objective:
To evaluate the impact of selective laser trabeculoplasty (SLT) on diurnal intraocular pressure (IOP) fluctuation in patients with open-angle glaucoma or ocular hypertension.
Approach:
- SLT resulted in sustained reductions in mean and maximum IOP, IOP range, and standard deviation through 18 months.
- Statistically significant differences in IOP parameters were observed at all post-treatment time points.
- A significant proportion of maximum IOP values occurred outside typical clinic hours, indicating potential underestimation of IOP variability in clinical settings.
- The greatest reduction in mean IOP was noted in the early morning hours.
- Attrition of participants due to loss to follow-up, medication changes, or repeat SLT.
- No significant predictors identified for IOP fluctuation reduction post-SLT.
Key Findings:
Interpretation:
SLT may provide comprehensive pressure stabilization beyond single clinic measurements, with durable IOP-lowering effects observed over 18 months.
Limitations:
Conclusion:
Measures of IOP fluctuation significantly decreased through 18 months after SLT, highlighting the effectiveness of home tonometry in assessing treatment response.
Sources:
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